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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SOX10 All Species: 26.36
Human Site: Y427 Identified Species: 58
UniProt: P56693 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P56693 NP_008872.1 466 49911 Y427 G L Y S A F S Y M G P S Q R P
Chimpanzee Pan troglodytes Q9BG89 509 56105 N424 Q I A Y S P F N L P H Y S P S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538379 621 66196 Y582 G L Y S A F S Y M G P S Q R P
Cat Felis silvestris
Mouse Mus musculus Q04888 466 49931 Y427 G L Y S A F S Y M G P S Q R P
Rat Rattus norvegicus O55170 466 50021 Y427 G L Y S A F S Y M G P S Q R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519755 494 53531 Y455 S L Y S A F S Y M G P S Q R P
Chicken Gallus gallus Q9W757 461 49839 Y422 G L Y S A F S Y M G P S Q R P
Frog Xenopus laevis Q8AXX8 446 49080 Y408 S L Y S A F S Y M G P P Q R P
Zebra Danio Brachydanio rerio Q6RVD7 245 26782 P207 G N P G Y M I P C N C A A W P
Tiger Blowfish Takifugu rubipres NP_001072112 462 50618 F423 G L Y Q Y P Y F H S S R R P Y
Fruit Fly Dros. melanogaster P40657 784 84853 Q639 T A A S Y Y T Q L P Y P P T S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.6 N.A. 74.4 N.A. 98.5 97.4 N.A. 64.7 85.1 72.9 23.1 48 22 N.A. N.A. N.A.
Protein Similarity: 100 64 N.A. 74.7 N.A. 98.9 98 N.A. 70.2 89.6 79.4 33.4 61.5 33.7 N.A. N.A. N.A.
P-Site Identity: 100 0 N.A. 100 N.A. 100 100 N.A. 93.3 100 86.6 13.3 20 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 20 N.A. 100 N.A. 100 100 N.A. 93.3 100 86.6 20 33.3 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 19 0 64 0 0 0 0 0 0 10 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 64 10 10 0 0 0 0 0 0 0 % F
% Gly: 64 0 0 10 0 0 0 0 0 64 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 73 0 0 0 0 0 0 19 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 64 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 10 0 10 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 19 0 10 0 19 64 19 10 19 73 % P
% Gln: 10 0 0 10 0 0 0 10 0 0 0 0 64 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 10 64 0 % R
% Ser: 19 0 0 73 10 0 64 0 0 10 10 55 10 0 19 % S
% Thr: 10 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 73 10 28 10 10 64 0 0 10 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _